Posted on: 16 April 2019

TWO CNWL members of staff have co-authored a systematic review of studies of cognitive impairment in patients with Primary Sjögren’s Syndrome (pSS) – a rheumatic disease of autoimmune and inflammatory origin.

Marco Isetta, from the Trust’s Library and Knowledge Services, and Dr Jordi Serra-Mestres, Neuropsychiatrist and Consultant in Old Age Psychiatry, joined with three other researchers in a thorough investigation of all available studies.

Their systematic review has been published in the online journal Brain Sciences, and can be accessed at

Their findings confirmed the scarcity of adequate studies on cognitive function in pSS. The paper concludes: “Routine assessment of cognitive function in patients with pSS seems advisable and it will help to elucidate some of the unmet needs highlighted by this review in future appropriately designed studies.”